In enzymology, aldose reductase (or aldehyde reductase) (EC 126.96.36.199) is a cytosolic NADPH-dependent oxidoreductase that catalyzes the reduction of a variety of aldehydes and carbonyls, including monosaccharides. It is primarily known for catalyzing the reduction of glucose to sorbitol, the first step in polyol pathway of glucose metabolism.
Aldose reductase, Recombinant (Human)
Enzyme Commission Number
Aldehyde reductase; Aldo-keto reductase family 1 member B1