The three isoenzymes (MM, MB, and BB) are found in muscle, cardiac and brain tissues. These recombinant proteins are ideal for calibrating diagnostic instruments and researching neuromuscular diseases. Creatine Kinases can be used for indications in many neuromuscular applications. These disorders include cardiac disease, mitochondrial disorders, inflammatory myopathies, myasthenia, polymyositis, McArdle's disease, NMJ disorders, muscular dystrophy, ALS, hypo and hyperthyroid disorders, central core disease, acid maltase deficiency, myoglobinuria, rhabdomyolysis, motor neuron diseases, rheumatic diseases, and other that create elevated or reduced levels of Creatine Kinases.
CKMBT1, Recombinant (Human)
CKMBT1; CKMBITI; CKMBI; CKMB
Sterile Filtered colourless liquid formulation.
CKMBITI Human Recombinant produced in Pichia Pastoris is a glycosylated polypeptide chain having an identical amino acid sequence compared to the native enzyme, purified under non-denaturing conditions and reacts with polyclonal antibodies to MB Isoenzyme in ELISA. The CKMBITI is purified by proprietary chromatographic techniques.
Greater than 95.0% as determined by (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
CKMBITI although stable at 15°C for 7 days, should be stored below -18°C. Please prevent freeze-thaw cycles.
The protein (10 mg/ml) contains 20mM Sodium Phosphate, pH-8.
Creatine Kinase MB Isoenzyme Type-I; Creatine Kinase MB Isoenzyme Type-1; CKMBITI; CKMBI; CKMB; CKMBT1