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Enzymes for Research, Diagnostic and Industrial Use

Farnesyl Proteintransferase from Rat, Recombinant

Cat No.
NATE-0836
Description
A heterodimeric enzyme that catalyzes the transfer of a 15-carbon isoprenoid group to a variety of cellular proteins including Ras.
Abbr
FPTase, Recombinant (Rat)
Alias
FPTase
Source
E. coli
Species
Rat
Product Overview
Recombinant, rat FPTase expressed in E. coli A heterodimeric enzyme that catalyzes the transfer of a 15-carbon isoprenoid group to a variety of cellular proteins including Ras. Recognizes the C-terminal CAAX cysteine motif where the farnesylated cysteine is followed by two aliphatic amino acids and either leucine or serine.
Form
Liquid
Activity
1 pmol of FPTase will transfer 1 pmol of farnesyl to H-Ras in 15 min at 37°C.
Molecular Weight
α-subunit: ~48 kDa; β-subunit: ~46 kDa
Purity
>85% by SDS-PAGE
Storage
< -70°C; Avoid freeze/thaw
Buffer
In 40 mM NaCl, 25 mM HEPES, 5 mM DTT, pH 7.2.
Synonyms
Farnesyl Proteintransferase; FTase
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