Glycogen synthase kinase-3 is a serine-threonine protein kinase involved in regulation of metabolic enzymes such as glycogen synthase and ATP-Citrate lyase, and of protein phosphatase-1. It also phosphorylates brain tau-proteins, inducing an Alzheimer-like state, and protooncogene transcription factors. GSK-3β is one of two isozymes.
GSK3B, Recombinant (Rabbit)
> 90% (SDS-PAGE), recombinant, expressed in E. coli
One unit will transfer one pmole of phosphate from ATP to phosphatase inhibitor 2 per min at pH 7.5 at 30°C.
Glycogen Synthase Kinase 3β; GSK-3β; GSK3B; 9059-09-0