In enzymology, a guanylate kinase (EC 126.96.36.199) is an enzyme that catalyzes the chemical reaction:ATP + GMP↔ ADP + GDP. Thus, the two substrates of this enzyme are ATP and GMP, whereas its two products are ADP and GDP. This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with a phosphate group as acceptor. This enzyme participates in purine metabolism.
GMP kinase, Native (Bovine)
Lyophilized powder containing potassium phosphate buffer salts
Enzyme Commission Number
10-40 units/mg protein
One unit will convert 1.0 μmole each of GMP and ATP to GDP and ADP per min at pH 7.5 at 30°C.
Abacavir metabolism, organism-specific biosystem; Guanine ribonucleotide biosynthesis IMP => GDP,GTP, organism-specific biosystem; Metabolism of nucleotides, organism-specific biosystem
ATP binding; guanylate kinase activity
guanylate kinase; deoxyguanylate kinase; 5'-GMP kinase; GMP kinase; guanosine monophosphate kinase; ATP:GMP phosphotransferase; EC 188.8.131.52; 9026-59-9