In enzymology, a guanylate kinase (EC 22.214.171.124) is an enzyme that catalyzes the chemical reaction:ATP + GMP↔ ADP + GDP. Thus, the two substrates of this enzyme are ATP and GMP, whereas its two products are ADP and GDP. This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with a phosphate group as acceptor. This enzyme participates in purine metabolism.
GMP kinase, Native (Porcine)
buffered aqueous glycerol solution; Solution in 50% glycerol, 1 mM potassium phosphate, pH approx. 7.0, containing 0.1 mm EDTA
Enzyme Commission Number
> 10 units/mg protein (modified Warburg-Christian)
One unit will convert 1.0 μmole each of GMP and ATP to GDP and ADP per min at pH 7.5 at 30°C.
guanylate kinase; deoxyguanylate kinase; 5'-GMP kinase; GMP kinase; guanosine monophosphate kinase; ATP:GMP phosphotransferase; EC 126.96.36.199; 9026-59-9