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Native Rat Protein Kinase C

Cat No.
NATE-0573
Description
Protein kinase C is a family of protein kinase enzymes that are involved in controlling the function of other proteins through the phosphorylation of hydroxyl groups of serine and threonine amino acid residues on these proteins. PKC enzymes in turn are activated by signals such as increases in the concentration of diacylglycerol (DAG) or calcium ions (Ca2+). Hence PKC enzymes play important roles in several signal transduction cascades.
Abbr
PKC, Native (Rat)
Alias
PKC
Source
Rat brain
Species
Rat
Form
Type I, buffered aqueous glycerol solution; Type II, lyophilized powder.
Enzyme Commission Number
EC 2.7.1.37
Activity
Type I, 50-200 units/mL
CAS No.
141436-78-4
Molecular Weight
mol wt 82 kDa by SDS-PAGE
Purity
> 90% (SDS-PAGE)
Unit Definition
One unit will transfer 1 nmol of phosphate per min from ATP to histone H1 at pH 7.4 at 30°C.
Stability
−70°C
Buffer
Solution in 50% glycerol containing 20 mM Tris, pH 7.5, 0.5 mM EDTA, 0.5 mM EGTA, 5 mM DTT, 100 mM NaCl, 0.02% Tween 20, and 1 μg/ml leupeptin.
Synonyms
EC 2.7.11.13; 141436-78-4; Protein kinase C; PKC; calcium-dependent protein kinase C; calcium-independent protein kinase C; calcium/phospholipid dependent protein kinase; cPKCα; cPKCβ; cPKCγ; nPKCδ; nPKCε; nPKCη; nPKCθ; PKCα; PKCβ; PKCγ; PKCδ; PKCε; PKCζ; Pkc1p; protein kinase Cε; STK24
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