Products

Enzymes for Research, Diagnostic and Industrial Use

S-methyl-5'-thioadenosine phosphorylase from Human, Recombinant

Cat No.
NATE-0462
Description
MTAP expression is crucial for the catabolism of methylthioadenosine, which is a by-product of polyamine biosynthesis in the methionine salvage pathway. Protein expression is decreased by homozygous deletion and promoter hypermethylation.
Abbr
MTAP, Recombinant (Human)
Alias
MTAP
Source
E. coli
Species
Human
Applications
S-methyl-5′-thioadenosine phosphorylase human (MTAP) is an enzyme used in cancer research that is deficient in many types of cancer. Decreased MTAP expression may be used as a potential indicator of disease progression of gastrointestinal stromal tumors. MTAP may be a used to develop potential therapeutic strategies for hepat ocellular carcinoma (HCC) since MTAP inactivation has been linked to HCC development and invasiveness
Product Overview
N-terminal GST-tagged 57 kDa protein containing amino acids 2-end.
Form
Supplied as a solution in 25 mM Tris-HCl, pH 8.0,100 mM NaCl, 0.05% Tween-20, 10% glycerol,and 3 mM DTT.
Enzyme Commission Number
EC 2.4.2.28
CAS No.
61970-06-7
Molecular Weight
57 kDa
Storage
−70°C
Synonyms
S-methyl-5'-thioadenosine phosphorylase; EC 2.4.2.28; 5'-deoxy-5'-methylthioadenosine phosphorylase; MTA phosphorylase; MeSAdo phosphorylase; MeSAdo/Ado phosphorylase; methylthioadenosine phosphorylase; methylthioadenosine nucleoside phosphorylase; 5'-methylthioadenosine:phosphate methylthio-D-ribosyl-transferase; S-methyl-5-thioadenosine phosphorylase; S-methyl-5-thioadenosine:phosphate S-methyl-5-thio-α-D-ribosyl-transferase; MTAP
Download Datasheet:


“MTAP” Total Products Page

Inquiry
Realted Products
Catalog
ProductName
EC No.
CAS No.
Source
Price
CatalogEXWM-2655
EC No.EC 2.4.2.28
CAS No.61970-06-7
Source
Online Inquiry
Name:
*Phone:
*E-mail Address:
Country:
Company/Institution:
*Products or Services Interested:
Quantity:
Project Description:
*Verification Code:
Please input "enzymes"(case insensitive) as verification code.

Welcome! For price inquiries, please feel free to contact us through the form below through the form on the left side. We will get back to you as soon as possible.

Sitemap  Privacy Policy
Copyright ©2011 - 2017 Creative Enzymes.
Contact Us 45-1 Ramsey Road, Shirley, NY 11967, USA
Email: info@creative-enzymes.com
Tel: 1-631-562-8517 1-631-448-7888
Fax: 1-631-938-8127
Distributors To view the contact information for a specific location, select the desired country: