Products

Enzymes for Research, Diagnostic and Industrial Use

Products
Online Inquiry

Our Products Cannot Be Used As Medicines Directly For Personal Use.

24 hour
Promise

Welcome! For price inquiries, please feel free to contact us through the form on the left side. We will get back to you as soon as possible.

Class A CpG oligonucleotide (Mouse specific)

Cat No.
LIGC-010
Description
CpG ODNs are synthetic oligonucleotides that contain unmethylated CpG dinucleotides in specific sequence contexts (CpG motifs). These CpG motifs are present at a 20-fold greater frequency in bacterial DNA than in mammalian DNA. CpG ODNs are recognized by Toll-like receptor 9 (TLR9), which leads to strong immunostimulatory effects.
ODN 1585 is a class A CpG ODN specific for mouse TLR9. Class A CpG ODNs are characterized by a central, phosphodiester, CpG-containing palindromic motif and a 3'phosphorothioate poly-G string.They induce high IFN-α production from plasmacytoid dendritic cells (pDCs) but are weak stimulators of TLR9-dependent NF-κB signaling.
Form
Lyophilized powder
Concentration
Working concentration: 1-5 µm
Specificity
murine TLR9 agonist
Storage
Upon receipt, store at -20 °C.
Synonyms
CpG oligonucleotides; ODNs; ODN 1585; CpG ODNs; CpG
Solubility
5 mg/ml in water
Substrates
Factor Xa
0
Click unfold / close
Inquiry Basket
Delete selected Quote Check Out
Decide to move out of the shopping cart?
Sure No, Back

Please choose product!

< Go Back
You have already added to buy this product