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Native Bovine Superoxide Dismutase
Cat No.
NATE-0675
Description
Superoxide dismutase (SOD) catalyzes the dismutation of superoxide radicals to hydrogen peroxide and molecular oxygen. SOD plays a critical role in the defense of cells against the toxic effects of oxygen radicals. SOD competes with nitric oxide (NO) for superoxide anion (which reacts with NO to form peroxynitrite), thereby SOD promotes the activity of NO. SOD has also been shown to suppress apoptosis in cultured rat ovarian follicles, neural cell lines, and transgenic mice by preventing the conversion of NO to peroxynitrate, an inducer of apoptosis.
Abbr
SOD, Native (Bovine)
Alias
SOD; SODF; SOD-1
Source
Bovine erythrocytes
Species
Bovine
Form
lyophilized powder
Enzyme Commission Number
EC 1.15.1.1
Activity
Type I, > 3 ,000 units/mg protein; Type II, > 4,500 units/mg protein; Type III, 2,500-7 ,000 units/mg protein.
CAS No.
9054-89-1
Molecular Weight
mol wt 32.5 kDa
Unit Definition
One unit will inhibit reduction of Cytochrome c by 50% in a coupled system with xanthine oxidase at pH 7.8 at 25°C in a 3.0 mL reaction volume. Xanthine oxidase concentration should produce an initial ΔA550 of 0.025 ± 0.005 per min.
Storage
−20°C
Warnings
For assay method, see McCord, J.M. and Fridovich,I., J. Biol. Chem., 244, 6049 (1969).
Function
chaperone binding; copper ion binding; ubiquitin-protein transferase activity
Synonyms
Superoxide dismutases; EC 1.15.1.1; superoxidase dismutase; copper-zinc superoxide dismutase; Cu-Zn superoxide dismutase; ferrisuperoxide dismutase; superoxide dismutase I; superoxide dismutase II; SOD; Cu,Zn-SOD; Mn-SOD; Fe-SOD; SODF; SODS; SOD-1; SOD-2; SOD-3; SOD-4; hemocuprein; erythrocuprein; cytocuprein; cuprein ; hepatocuprein; 9054-89-1
Download
Download Datasheet| Catalog | Product Name | EC No. | CAS No. | Source | Price |
|---|---|---|---|---|---|
| NATE-1925 | Native Porcine Superoxide Dismutase | EC 1.15.1.1 | 9054-89-1 | Porcine | Inquiry |
| NATE-1910 | Native Bacillus stearothermophilus Superoxide Dismutase | EC 1.15.1.1 | 9054-89-1 | Bacillus stearothermophilus | Inquiry |
| NATE-1659 | Superoxide Dismutase A from Bacterial, Recombinant | EC 1.15.1.1 | E. coli | Inquiry | |
| NATE-1658 | Superoxide Dismutase 2 from Human, Recombinant | EC 1.15.1.1 | E. coli | Inquiry |