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Kallikrein

Official Full Name
Kallikrein
Background
Kallikreins are serine protease enzymes having various physiological functions. Kallikreins are implicated in carcinogenesis and have potenital as novel cancer disease biomarkers. KLK1 is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. KLK1 is functionally conserved in its ability to release the vasoactive peptide, Lys-bradykinin, from low molecular weight kininogen. Human Kallikrein-1, also called as Kallidinogenase, Kininogenase or Kininogenin, is an active protein enzyme present in saliva, pancreatic juices, and urine that catalyzes the proteolysis of bradykininogen to bradykinin. Kallikrein-1, which derived from human or porcine, have been used as drugs for a long time, they are mainly used in the treatment f light to medium hypertension and occlusion of cerebral and surrounding blood vessels.
Synonyms
KLK1; KLK-1; HK1; HK-1; KLKR; KLK6; Tissue Kallikrein; Hklk1; EC 3.4.21.35; Kidney/pancreas/salivary gland kallikrein; Kallikrein-1
Catalog Product Name EC No. CAS No. Source Price
EXWM-4249 clostripain EC 3.4.22.8 9028-00-6 Inquiry
EXWM-4129 tissue kallikrein EC 3.4.21.35 389069-73-2 Inquiry
EXWM-4128 plasma kallikrein EC 3.4.21.34 410538-33-9 Inquiry
NATE-0851 Kallikrein-1 from Human, Recombinant Pichia Pastoris Inquiry
NATE-0362 Native Porcine Kallikrein EC 3.4.21.35 9001-01-8 Porcine pancrea... Inquiry
NATE-0361 Native Human Kallikrein EC 3.4.21.34 9001-01-8 Human plasma Inquiry
NATE-0218 Native Mouse Endoproteinase Arg-C EC 3.4.21.35 82047-85-6 Mouse submaxill... Inquiry
NATE-0143 Native Clostridium histolyticum Clostripain EC 3.4.22.8 9028-00-6 Clostridium his... Inquiry