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PKC

Official Full Name
PKC
Background
Protein Kinase C (PKC) is a serine/threonine kinase that is activated intracellularly by signal transduction pathways that produce DAG from phosphatidylinositol diphosphate (PIP2) and phosphatidylcholine (PC) through the action of various activated phospholipases. Phorbol esters also stimulate PKC. At least 11 PKC isozymes have been identified that differ in primary structure, tissue distribution, subcellular localization, response to extracellular signals, and substrate specificity. The isozymes can be grouped into three subfamilies. Members of the first family require Ca2+ and phospholipid and include PKCα, βI, βII, and γ. Members of the second family are phospholipid-dependent but Ca2+-independent, and include PKCδ, ε, η, and θ. Members of the third family are not activated by either DAG or phorbol esters and include PKCξ, μ, and ι.
Synonyms
PRKCZ; protein kinase C# zeta; protein kinase C zeta type; PKC2; PKC-ZETA; EC 2.7.1.37
Catalog Product Name EC No. CAS No. Source Price
NATE-0579 Native Bovine Protein Kinase G Iα EC 2.7.1.37 bovine lung Inquiry
NATE-0575 Protein Kinase Cε isozyme human, Recombinant EC 2.7.1.37 baculovirus inf... Inquiry
NATE-0576 Protein Kinase Cη isozyme human, Recombinant EC 2.7.1.37 baculovirus inf... Inquiry
NATE-0574 Protein kinase Cα isozyme human, Recombinant baculovirus inf... Inquiry
NATE-0573 Native Rat Protein Kinase C EC 2.7.1.37 141436-78-4 Rat brain Inquiry
NATE-0578 Native Rat Protein Kinase C Catalytic Subunit rat brain Inquiry
NATE-0577 Protein Kinase Cι, Active human, Recombinant E. coli Inquiry
NATE-0625 Protein Kinase Cζ isozyme from human, Recombinant EC 2.7.1.37 Baculovirus inf... Inquiry
NATE-0624 Protein kinase Cγ isozyme from human, Recombinant EC 2.7.1.37 Baculovirus inf... Inquiry
NATE-0623 Protein Kinase Cδ isozyme from human, Recombinant EC 2.7.1.37 Baculovirus inf... Inquiry
NATE-0622 Protein Kinase CβII isozyme from human, Recombinant EC 2.7.1.37 Baculovirus inf... Inquiry
NATE-0621 Protein Kinase CβI isozyme from human, Recombinant EC 2.7.1.37 Baculovirus inf... Inquiry