Products

Enzymes for Research, Diagnostic and Industrial Use

α-(1-2,3,4,6)-L-Fucosidase from Homo sapiens, Recombinant

Cat No.
NATE-1067
Description
Alpha-Fucosidase is an enzyme that breaks down fucose. Fucosidosis is an autosomal recessive lysosomal storage disease caused by defective alpha-L-fucosidase with accumulation of fucose in the tissues. Different phenotypes include clinical features such as neurologic deterioration, growth retardation, visceromegaly, and seizures in a severe early form; coarse facial features, angiokeratoma corporis diffusum, spasticity and delayed psychomotor development in a longer surviving form; and an unusual spondylometaphyseoepiphyseal dysplasia in yet another form.
Abbr
FUCA, Recombinant (Homo sapiens)
Alias
FUCA
Source
Homo sapiens
Applications
High purity α-(1-2,3,4,6)-L-Fucosidase (Homo sapiens) for use in research, biochemical enzyme assays and in vitro diagnostic analysis.
Form
In 3.2 M ammonium sulphate.
Enzyme Commission Number
EC 3.2.1.51
Activity
7 U/mg protein (on pNP-α-L-fucopyranoside) at pH 4.0 and 25°C; ~ 23 U/mg protein (on pNP-α-L-fucopyranoside) at pH 4.0 and 37°C; ~ 68 U/mg protein (on pNP-α-L-fucopyranoside) at pH 4.0 and 50°C.
CAS No.
9037-65-4
Molecular Weight
~ 52,000
Isoelectric point
~ 6.3
pH Stability
4.0-9.0
Specificity
Broad specificity; hydrolysis of terminal non-reducing α-(1-2,3,4,6)-linked L-fucose residues from glycoproteins and oligosaccharides.
Unit Definition
One Unit of α-L-fucosidase activity is defined as the amount of enzyme required to release one µmole of p-nitrophenol (pNP) per minute from p-nitrophenyl-α-L-fucopyranoside (1 mM) in sodium acetate buffer (100 mM) at pH 4.0 at the temperatures indicated.
Optimum pH
3.0-4.0
Optimum temperature
50°C
Thermal stability
up to 60°C
Stability
> 2 years at 4°C.
Storage
4°C
Preparation Instructions
For assay, this enzyme should be diluted in sodium acetate buffer (100 mM), pH 4.0 containing 1 mg/mL BSA. Swirl to mix the enzyme immediately prior to use.
Synonyms
α-L-fucoside fucohydrolase; Alpha-Fucosidase; FUCA1; FUCA; EC 3.2.1.51
Download Datasheet:


“FUCA” Total Products Page

Inquiry
Realted Products
Catalog
ProductName
EC No.
CAS No.
Source
Price
CatalogNATE-0259
EC No.EC 3.2.1.51
CAS No.9037-65-4
Source
CatalogNATE-0260
EC No.
CAS No.
SourceAlmond meal
CatalogNATE-0261
EC No.
CAS No.
SourceBovine kidney
CatalogNATE-0262
EC No.EC 3.2.1.51
CAS No.9037-65-4
SourceXanthomonas sp.
+ See More >>
Realted Service
Realted Protocols
alfa-L-fucosidase -Enzymatic Assay Protocol
Online Inquiry
Name:
*Phone:
*E-mail Address:
Country:
Company/Institution:
*Products or Services Interested:
Quantity:
Project Description:
Our Products are Not Intended for Private Therapeutic Use!
*Verification Code:
Please input "enzymes"(case insensitive) as verification code.

Welcome! For price inquiries, please feel free to contact us through the form below through the form on the left side. We will get back to you as soon as possible.

Sitemap  Privacy Policy
Copyright ©2011 - 2017 Creative Enzymes.
Contact Us 45-1 Ramsey Road, Shirley, NY 11967, USA
Email: info@creative-enzymes.com
Tel: 1-631-562-8517 1-631-448-7888
Fax: 1-631-938-8127
Distributors To view the contact information for a specific location, select the desired country: