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(R)-MG132

Cat No.
CEI-1002
Description
(R)-MG132 is a potent, cell permeable and reversible inhibitor of proteasomes. It can inhibit proteasome activity in lysates of J558L multiple myeloma cells and EMT6 breast cancer cells. In comparison to (S)-MG132, the (R)-MG132 stereoisomer is a more effective inhibitor of chymotrypsin-like (ChTL), trypsin-like (TL), and peptidylglutamyl peptide hydrolyzing proteasome (PGPH) activities.
Abbr
(R)-MG132(ChTL, TLa, PGPH)
Appearance
A crystalline solid.
CAS No.
1211877-36-9
Molecular Weight
475.6
Purity
>98%
Storage
Store at or below -20 centigrade for up to two years.
Targets
ChTL, TLa, PGPH
IC50
0.22 µM, 34.4 µM, 2.95 µM
Molecular Formula
C26H41N3O5
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