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4-Methylumbelliferyl palmitate

Cat No.
CSUB-0679
Description
Cholesterol ester storage disease and Wolman disease are recessive autosomal disorders caused by a deficiency in lysosomal acid lipase (LAL), also known as cholesteryl ester hydrolase. 4-Methylumbelliferyl palmitate (4-MUP) is a fluorogenic substrate for LAL. It may also be cleaved by other acid lipases. Recent advances allow the assessment of LAL activity in very small blood volumes using 4-MUP.
Applications
A fluorogenic substrate for lipase in human leukocytes
Form
Solid
CAS No.
17695-48-6
Molecular Weight
414.59
Purity
>97%
Storage
Store at -20° C
Synonyms
4-MU-palmitate; palmitic acid 4-methylumbelliferyl ester
Molecular Formula
C26H38O4
MDL Number
MFCD00037612
Melting Point
77° C (lit.)
Solubility
Soluble in water (partly).
Substrates
Phosphatase
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