Products

Enzymes for Research, Diagnostic and Industrial Use

Products
Online Inquiry

Our Products Cannot Be Used As Medicines Directly For Personal Use.

24 hour
Promise

Welcome! For price inquiries, please feel free to contact us through the form on the left side. We will get back to you as soon as possible.

A83-01

Cat No.
CEI-0952
Description
Potent and selective ALK4, 5 and 7 inhibitor. IC50=45, 12, 7.5 nM respectively. Prevents phosphorylation of Smad2/3 and growth inhibition induced by TGFβ. Inhibits differentiation of rat induced pluripotent stem cells and increases clonal expansion efficiency. Together with AMI-5 enabled Oct4-induced reprogramming of mouse embryonic fibroblasts. Active in rat models. Cell permeable
Abbr
A83-01(ALK)
Alias
3-(6-Methyl-2-pyridinyl)-N-phenyl-4-(4-quinolinyl)-1H-pyrazole-1-carbothioamide
Appearance
Light Yellow powder
Product Overview
ALK inhibitor
CAS No.
909910-43-6
Molecular Weight
421.5
Purity
>98% (TLC); NMR (Conforms)
Synonyms
3-(6-Methyl-2-pyridinyl)-N-phenyl-4-(4-quinolinyl)-1H-pyrazole-1-carbothioamide
Targets
ALK
Molecular Formula
C25H19N5S
Solubility
May be dissolved in DMSO (20mg/ml)
0
Click unfold / close
Inquiry Basket
Delete selected Quote Check Out
Decide to move out of the shopping cart?
Sure No, Back

Please choose product!

< Go Back
You have already added to buy this product