Products

Enzymes for Research, Diagnostic and Industrial Use

A83-01


Cat No.
CEI-0952
Description
Potent and selective ALK4, 5 and 7 inhibitor. IC50=45, 12, 7.5 nM respectively. Prevents phosphorylation of Smad2/3 and growth inhibition induced by TGFβ. Inhibits differentiation of rat induced pluripotent stem cells and increases clonal expansion efficiency. Together with AMI-5 enabled Oct4-induced reprogramming of mouse embryonic fibroblasts. Active in rat models. Cell permeable
Abbr
A83-01(ALK)
Alias
3-(6-Methyl-2-pyridinyl)-N-phenyl-4-(4-quinolinyl)-1H-pyrazole-1-carbothioamide
Appearance
Light Yellow powder
Product Overview
ALK inhibitor
CAS No.
909910-43-6
Molecular Weight
421.5
Purity
>98% (TLC); NMR (Conforms)
Synonyms
3-(6-Methyl-2-pyridinyl)-N-phenyl-4-(4-quinolinyl)-1H-pyrazole-1-carbothioamide
Targets
ALK
Molecular Formula
C25H19N5S
Solubility
May be dissolved in DMSO (20mg/ml)
Download Datasheet:



Inquiry
Related Products
Catalog
ProductName
EC No.
CAS No.
Source
Price
CatalogCEI-0022
ProductNameCH5424802
EC No.
CAS No.1256580-46-7
Source
CatalogCEI-0836
ProductNameLDK378
EC No.
CAS No.1032900-25-6
Source
CatalogCEI-0871
ProductNameAZD3463
EC No.
CAS No.1356962-20-3
Source
Online Inquiry
Name:
*Phone:
*E-mail Address:
Country or Region:
Company/Institution:
*Products or Services of Interest:
Quantity:
Project Description:
Our Products Are Not Intended For Clinical Use.
*Verification Code:
Verification code

Welcome! For price inquiries, please feel free to contact us through the form on the left side. We will get back to you as soon as possible.


Sitemap | Privacy Policy | Terms and Conditions
Copyright ©2011 - 2021 Creative Enzymes.
Contact Us address-USA
Email: info@creative-enzymes.com
Tel:
Fax: fax
Distributors To view the contact information for a specific location, select the desired country or region:
     
0
Click unfold / close
Inquiry Basket
Delete selected Check Out
Decide to move out of the shopping cart??

Sure No, Back
 

Please choose product!

< Go Back
You have already added to buy this product