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AG-1478

Cat No.
CEI-0955
Description
Potent and selective inhibitor of the EGFR kinase IC50 = 3 nM. Inhibits proliferation of a variety human cancer cell lines. Reduces pulmonary fibrosis in a rat model. Cell permeable.
Abbr
AG-1478(EGFR)
Alias
1. N-(3-Chlorophenyl)-6, 7-dimethoxy-4-quinazolinanine
Appearance
Off white powder
Product Overview
EGFR inhibitor
CAS No.
175178-82-2
Molecular Weight
315.8
Purity
>98% (TLC); NMR (Conforms)
Synonyms
1. N-(3-Chlorophenyl)-6,7-dimethoxy-4-quinazolinanine
Targets
EGFR
Molecular Formula
C16H14ClN3O2
Melting Point
177-178ºC
Solubility
May be dissolved in DMSO (30 mg/ml); or Ethanol (10 mg/ml, warm)
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