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AGI-5198

Cat No.
CEI-0995
Description
AGI-5198 is a selective inhibitor of IDH1 R132H and R132C mutants. It serves as a potent antitumor compound by inducing demethylation of histone H3K9me3 and expression of genes associated with gliogenic differentiation.
Abbr
AGI-5198(IDH1)
Alias
IDCD, IDH, IDP, IDPC, PICD
Appearance
A crystalline solid.
CAS No.
1355326-35-0
Molecular Weight
462.56
Purity
> 95%
Storage
Room temperature for 24 months as powder, +4 centigrade for 2 weeks in DMSO, or −70 centigrade for 6 months in anhydrous DMSO. Keep DMSO stock solutions out of contact with air. Protect from moisture.
Synonyms
IDCD, IDH, IDP, IDPC, PICD
Targets
IDH1, R132H/R132C
IC50
0.07 μM/0.16 μM
Molecular Formula
C27H31FN4O2
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