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Enzymes for Research, Diagnostic and Industrial Use

AMG-208

Cat No.
CEI-0034
Description
AMG-208
CAS No.
1002304-34-8
Molecular Weight
383.4
Purity
>99%
Storage
2 years at -20 centigrade
Targets
c-Met
Molecular Formula
C22H17N5O2
Solubility
No
In vitro
As a selective inhibitor, AMG-208 can potently inhibit c-Met with IC50 of 9.3 nM. In PC3 cells, AMG-208 also can induce inhibition to c-Met phosphorylation mediated by HGF with IC50 of 46 nM.
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