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Abiraterone Acetate (CB7630)

Cat No.
CEI-0228
Description
Abiraterone Acetate (CB7630)
Alias
CB 7630, CB-7630
CAS No.
154229-18-2
Molecular Weight
391.55
Purity
>99%
Storage
2 years at -20 centigrade
Synonyms
CB 7630, CB-7630
Targets
cytochrome P45017alpha
Molecular Formula
C26H33NO2
Solubility
No
In vitro
Abiraterone (17-(3-pyridyl)androsta-5,16-dien-3beta-ol, 1) is a potent inhibitor (IC50 4 nM for hydroxylase) of human cytochrome P45017alpha. Abiraterone acetate is a selective, irreversible inhibitor of CYP17 and can suppress adrenal synthesis of androgen precursors, and possibly in situ steroidogenesis in the tumor microenvironment.Abiraterone inhibits both testicular and extratesticular androgen synthesis.
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