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Abl Kinase Mutant active human, Recombinant


Cat No.
NATE-0013
Description
Abelson murine leukemia viral oncogene homolog 1 also known as ABL1 is a protein that, in humans, is encoded by the ABL1 gene (previous symbol ABL) located on chromosome 9. c-Abl is sometimes used to refer to the version of the gene found within the mammalian genome, while v-Abl refers to the viral gene.
Abbr
ABL1, Recombinant (Human)
Alias
ABL1; ABL; c-ABL; v-abl
Source
Baculovirus infected Sf9 cells
Species
Human
Product Overview
Human Abelson murine leukemia viral oncogene homolog 1 (Abl-1) (GenBank Accession No. NM_007313), amino acids 248-531 with T334I mutation and N-terminal His-tag, MW = 33 kDa, expressed in a Baculovirus-infected Sf9 cell expression system
Form
aqueous solution
Molecular Weight
mol wt 33 kDa
Stability
−70°C
Pathway
Alpha6-Beta4 Integrin Signaling Pathway, organism-specific biosystem; Axon guidance, organism-specific biosystem; Axon guidance, conserved biosystem; Axon guidance, organism-specific biosystem; CDO in myogenesis, organism-specific biosystem; Cell cycle, organism-specific biosystem; Cell cycle, organism-specific biosystem
Function
ATP binding; DNA binding; SH3 domain binding; actin monomer binding; kinase activity; magnesium ion binding; manganese ion binding; mitogen-activated protein kinase binding; nicotinate-nucleotide adenylyltransferase activity; non-membrane spanning protein tyrosine kinase activity; nucleotide binding; proline-rich region binding; protein C-terminus binding; protein binding; protein tyrosine kinase activity; receptor activity
Synonyms
ABL1; JTK7; c-ABL; p150; Abl Kinase; ABL; bcr/abl; c-ABL1; v-abl
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