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Apremilast

Cat No.
CEI-0616
Description
Apremilast is a potent PDE4 (phosphodiesterase 4) inhibitor (IC50 = 74 nM). It reduces TNF-α production in human synovial cells and significantly suppresses experimental arthritis.
Appearance
Yellow solid
Product Overview
A potent PDE4 (phosphodiesterase 4) inhibitor
CAS No.
608141-41-9
Molecular Weight
602.8
Purity
>95% by TLC
Storage
-20 centigrade
Targets
PDE1a, PDE2A, PDE3A, PDE4A, PDE5A
Molecular Formula
C 22 H 24 N 2 O 7 S
Chemical Name
N-{2-[(1S)-1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl}acetamide
Solubility
DMSO (25 mg/ml) or EtOH (25 mg/ml)
Shipping Conditions
Gel pack
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