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Atorvastatin

Cat No.
CEI-0532
Description
A cholesterol lowering drug and a competitive inhibitor of HMG-CoA (3-hydroxy-3-methylglutaryl coenzyme A) reductase (IC50 = 154 nM) a rate limiting enzyme in cholesterol synthesis. Blocks the production of mevalonate, a critical compound in the production of cholesterol and isoprenoids. In addition to inhibiting cholesterol synthesis, atorvastatin reduces the production of low-density lipoprotein (LDL).
Appearance
White solid
Product Overview
A potent HMG-CoA reductase inhibitor
CAS No.
134523-00-5
Molecular Weight
164.28
Purity
>98%
Storage
+4C
Targets
HMG-CoA
Molecular Formula
C33H35FN2O5
Chemical Name
2-​(4-​fluorophenyl)-​βR,​δR-​dihydroxy-​5-​(1-​methylethyl)-​3-​phenyl- ​4-​[(phenylamino)carbonyl]-​1H-​pyrrole-​1-​heptanoic acid
Solubility
DMSO (15 mg/ml) and H₂O (1 mg/ml)
Shipping Conditions
RT
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