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atrolysin E

Cat No.
EXWM-4326
Description
A 25.7 kDa hemorrhagic endopeptidase from the venom of the western diamondback rattlesnake (Crotalus atrox) that digests basement membrane components, including the triple helix of type IV collagen. Such action is believed to contribute to the hemorrhagic property by weakening capillary walls. In peptidase family M12 (astacin family)
Form
Liquid or lyophilized powder
Enzyme Commission Number
CAS No.
172306-51-3
Storage
Store it at +4 ºC for short term. For long term storage, store it at -20 ºC~-80 ºC.
Synonyms
Crotalus atrox metalloendopeptidase e; hemorrhagic toxin e
Reaction
Cleavage of Asn3┼Gln, Ser9┼His and Ala14┼Leu bonds in insulin B chain and Tyr14┼Gln and Thr8┼Ser in A chain. Cleaves type IV collagen at Ala73┼Gln in α1(IV) and at Gly7┼Leu in α2(IV)
Notes
This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
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