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BCl-2 Inhibitor, ABT-199

Cat No.
CEI-0407
Description
Cell-permeable. A potent and selective BCl-2 inhibitor that spares platelets while achieving potent antitumor activity.
Alias
GDC-0199
Appearance
White to yellowish solid
Product Overview
A potent BCl-2 inhibitor
CAS No.
1257044-40-8
Molecular Weight
186.2
Purity
>99% by HPLC
Storage
-20 centigrade
Synonyms
GDC-0199
Targets
BCl-2
Molecular Formula
C 45 H 50 ClN 7 O 7 S
Chemical Name
2-((1H-Pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((4’-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1’-biphenyl]-2-yl)methyl)piperazin-1-yl)-N-((3-nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)phenyl)sulfonyl)benzamide
Solubility
DMSO ( 100 mM) and H₂O (100 mM)
Shipping Conditions
RT
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