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BML-259

Cat No.
CEI-0959
Description
Potent inhibitor of CDK5/p25 (IC50=64 nM). Inhibits CDK2/cyclin E at slightly higher concentration (IC50=98nM). Protects cells against NAC-amyloid-induced cell death. Cell permeable.
Abbr
BML-259 (CDK5, CDK5R1)
Alias
N-(5-Isopropylthiazol-2-yl) phenylacetamide
Appearance
White powder
Product Overview
CDK5/p25 inhibitor
CAS No.
267654-00-2
Molecular Weight
260.4
Purity
>98% (TLC: 5% CH3OH/CH2Cl2; Rf=0.46); NMR (Conforms)
Synonyms
N-(5-Isopropylthiazol-2-yl) phenylacetamide
Targets
CDK5/p25
Molecular Formula
C14H16N2OS
Melting Point
150-152ºC
Solubility
May be dissolved in DMSO (>25 mg/ml) or DMF (30 mg/ml)
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