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BMX-IN-1

Cat No.
CEI-1258
Description
BMX-IN-1 is a highly selective and potent irreversible inhibitor of BMX kinase.
Product Overview
BMX-IN-1 is a highly selective and irreversible inhibitor of BMX kinase. BMX, also known as ETK, is a member of Tec family and plays an important role in regulating ischemia-mediated arteriogenesis and lymphangiogenesis. BMX is mainly expressed in arterial endothelia and in myeloid hematopoietic cells and it has been reported that BMX involves in tumor growth. BMX-IN-1 is a potent BMX kinase inhibitor and has an irreversible function on BMX kinase. When tested with prostate cancer cell lines, BMX-IN-1 treatment inhibited the proliferation of Tel-BMX-transformed Ba/F3 cells at lowdose.
CAS No.
1431525-23-3
Molecular Weight
524.59
Purity
0.982
Storage
Store at -20°C
Synonyms
BMX kinase inhibitor
Targets
BMX kinase
Molecular Formula
C29H24N4O4S
Chemical Name
N-[5-[9-[4-(methanesulfonamido)phenyl]-2-oxobenzo[h][1,6]naphthyridin-1-yl]-2-methylphenyl]prop-2-enamide
Solubility
Soluble in DMSO
Shipping Conditions
Evaluation sample solution: ship with blue ice. All other available size: ship with RT, or blue ice upon request
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