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Bafilomycin A1

Cat No.
CEI-0697
Description
A highly potent and selective inhibitor of vacuolar H⁺-ATPases (V-ATPases) in vitro. It is effective in nanomolar concentrations in animal cells, plant cells and microorganisms; also selective over other ATP hydrolyzing enzymes such as F-ATPases, Ca²⁺ATPases, Na⁺K⁺ATPases and plasma membrane H⁺-ATPases. Also prevents autophagy at a late stage by inhibiting fusion between autophagosomes and lysosomes.
Appearance
White solid
Product Overview
An inhibitor of vacuolar H+-ATPases (V-ATPases)
CAS No.
88899-55-2
Molecular Weight
149.15
Purity
>98%
Storage
-20 centigrade
Targets
ATP6V0A4
Molecular Formula
C₃₅H₅₈O₉
Solubility
DMSO (50 mM)
Shipping Conditions
Gel pack
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