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Bayer-18

Cat No.
CEI-1130
Description
Bayer-18 is a selective TYK2 inhibitor, with an IC50=18.7nM on TYK2. The compound shows 1000 fold selectivity against JAK2, CDK and KDR.
Abbr
Bayer-18(TYK2)
Alias
JTK1
CAS No.
1251752-12-1
Molecular Weight
390.46
Purity
> 95%
Stability
2 years -20 centigrade Powder
1 month -4 centigrade in DMSO
More than one month -80 centigrade in DMSO
Storage
4 centigrade
Synonyms
JTK1
Targets
TYK2
Molecular Formula
C19H27FN6O2
Chemical Name
1-tert-butyl-3-[3-[[5-fluoro-4-[(2-hydroxy-1,1-dimethyl-ethyl)amino]pyrimidin-2-yl]amino]phenyl]urea
Solubility
DMSO > 112mg/mL Water >1mg/mL Ethanol > 4mg/mL
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