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Enzymes for Research, Diagnostic and Industrial Use

Bisindoylmaleimide X HCl

Cat No.
CEI-1087
Description
Bisindoylmaleimide X is a potent and selective protein kinase C (PKC) inhibitor (IC50 value of 15nM for rat brain PKC). It inhibits PKC within intact platelets and T cells. It also inhibits Fas-mediated apoptosis and T cell-mediated autoimmune diseases.
Abbr
Bisindoylmaleimide X HCl(DYT10)
Alias
EKD1, PKC
Product Overview
Protein kinase C (PKC) inhibitor
CAS No.
145317-11-9
Molecular Weight
460.96
Purity
> 95%
Stability
2 years -20 centigrade Powder
1 month -4 centigrade in DMSO
More than one month -80 centigrade in DMSO
Storage
4 centigrade
Synonyms
EKD1, PKC
Targets
PKC
Molecular Formula
C26H24N4O2.HCl
Chemical Name
3-(8-(aminomethyl)-6,7,8,9-tetrahydropyrido [1,2-a]indol-10-yl)-4-(1-methyl-1H-indol-2-yl)
-1H-pyrrole-2,5-dione hydrochloride
Solubility
DMSO > 112mg/mL Water >1mg/mL Ethanol > 4mg/mL
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