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Enzymes for Research, Diagnostic and Industrial Use

CEP-33779

Cat No.
CEI-1142
Description
CEP-33779 is a highly selective, orally active inhibitor for JAK2 with IC50 of 1.8nM in enzyme and 61nM in cell, comparing to the inhibition for JAK3 with IC50 of 150nM.
Abbr
CEP-33779(JAK2, JAK3)
Alias
JTK10, THCYT3
CAS No.
1346168-57-7
Molecular Weight
462.57
Purity
> 95%
Stability
2 years -20 centigrade Powder
1 month -4 centigrade in DMSO
More than one month -80 centigrade in DMSO
Storage
4 centigrade
Synonyms
JTK10, THCYT3
Targets
JAK2, JAK3
IC50
61nM, 150nM
Molecular Formula
C24H26N6O2S
Chemical Name
N-(3-(4-methylpiperazin-1-yl)phenyl)-8-(4-(methylsulfonyl)phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine
Solubility
DMSO > 112mg/mL Water >1mg/mL Ethanol > 4mg/mL
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