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CGI1746

Cat No.
CEI-1145
Description
GCI1746 was identified as a selective and potent ATP-competitive BTK inhibitor with a IC50 of 1.9nM. It is specific for BTK, with around 1000-fold selectivity over Tec and Src family kinases.
Abbr
CGI1746(BTK)
Alias
RP1-164F3.2, AGMX1, AT, ATK, BPK, IMD1, PSCTK1, XLA
CAS No.
910232-84-7
Molecular Weight
579.69
Purity
> 95%
Stability
2 years -20 centigrade Powder
1 month -4 centigrade in DMSO
More than one month -80 centigrade in DMSO
Storage
4 centigrade
Synonyms
RP1-164F3.2, AGMX1, AT, ATK, BPK, IMD1, PSCTK1, XLA
Targets
BTK
IC50
1.9nM
Molecular Formula
C34H37N5O4
Chemical Name
4-(tert-butyl)-N-(2-methyl-3-(4-methyl-6-((4-(morpholine-4-carbonyl)phenyl)amino)-5-oxo-4,5-dihydropyrazin-2-yl)phenyl)benzamide
Solubility
DMSO > 112mg/mL Water >1mg/mL Ethanol > 4mg/mL
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