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CGP60474

Cat No.
CEI-1276
Product Overview
CGP60474 is a potent inhibitor of cyclin-dependent kinases (CDKs) with IC50 value of 17 nM for CDK1.It is also an inhibitor of Protein Kinase C (PKC). CDKs are a family of protein kinases regulating the cell cycle. PKC plays an important role in signal transductions, cellular proliferation and differentiation. CGP60474 was highly selective for PKC than other serine/threonine and tyrosine kinases and showed competitive kinetics relative to ATP.
CAS No.
164658-13-3
Molecular Weight
355.82
Purity
0.98
Storage
Store at -20°C
Synonyms
CGP-60474; CGP 60474
Targets
CDKs; PKC
Molecular Formula
C18H18ClN5O
Chemical Name
3-[[4-[2-(3-chloroanilino)pyrimidin-4-yl]pyridin-2-yl]amino]propan-1-ol
Solubility
Soluble in DMSO
Shipping Conditions
Evaluation sample solution: ship with blue ice. All other available size: ship with RT, or blue ice upon request
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