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Calpain Inhibitor II, ALLM
Cat No.
CEI-0412
Description
A cell-permeable inhibitor of calpain 1 (Ki = 120 nM) and calpain 2 (Ki = 230 nM). Also potently inhibits cathepsin B (Ki = 100 nM), and cathepsin L (Ki = 0.6 nM). Shown to induce caspase-dependent apoptosis in human acute lymphoblastic leukemia and non-Hodgkin’s Lymphoma cells.
Alias
Ac-LLM-CHO, N-Acetyl-Leu-Leu-Methional
Appearance
White solid
Product Overview
A Calpain inhibitor
CAS No.
136632-32-1
Molecular Weight
404.54
Purity
>98% by HPLC
Storage
-20 centigrade
Synonyms
Ac-LLM-CHO, N-Acetyl-Leu-Leu-Methional
Targets
calpain I, calpain II
Molecular Formula
C₁₉H₃₅N₃O₄S
Solubility
DMSO (25 mg/ml) or Ethanol (30 mg/ml)
Shipping Conditions
Gel pack
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