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Caspase-1 Inhibitor Z-YVAD-FMK

Cat No.
CEI-0424
Description
A synthetic peptide that irreversibly inhibits ICE (interleukin-1β converting enzyme, Ki = 0.76 nM) activity. YVAD is the specific recognition sequence for ICE/caspase-1. The inhibitor is designed as a methyl ester to facilitate cell permeability. (CAUTION: If the intended use is on purified or recombinant enzymes, esterase should be added to generate free carboxyl groups).
Alias
Z-YVAD-FMK, Caspase-1 Inhibitor (fluoromethylketone)
Appearance
Yellow solid
Product Overview
Caspase-1 inhibitor
Molecular Weight
223.28
Purity
>98% by HPLC
Storage
-20 centigrade
Synonyms
Z-YVAD-FMK, Caspase-1 Inhibitor (fluoromethylketone)
Targets
Caspase-1
Molecular Formula
C₃₁H₃₉FN₄O₉
Solubility
DMSO (~ 5 mg/ml)
Shipping Conditions
Gel pack
Amino Acid Sequence
Z-Tyr-Val-Ala-Asp(OMe)-FMK
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