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Caspase-13 Inhibitor LEED-FMK

Cat No.
CEI-0428
Description
A synthetic peptide inhibitor that inhibits caspase-13 and related caspase activity. FMK inhibitors are irreversible and non-toxic, and can be used in both in vivo and in vitro studies. The inhibitor is designed as a methyl ester to facilitate cell permeability. (CAUTION: If the intended use is on purified or recombinant enzymes, esterase should be added to generate free carboxyl groups).
Alias
Z-LEED-FMK, Caspase-13 Inhibitor (fluoromethylketone)
Appearance
Pale yellow solid
Product Overview
A caspase-13 inhibitor
Molecular Weight
296.54
Purity
>97% by titration
Storage
+4 centigrade
Synonyms
Z-LEED-FMK, Caspase-13 Inhibitor (fluoromethylketone)
Targets
caspase-13
Molecular Formula
C₃₂H₄₅FN₄O₁₂
Solubility
DMSO (~ 6 mg/ml) or Ethanol (~ 30 mg/ml)
Shipping Conditions
Gel pack
Amino Acid Sequence
Z-Leu-Glu(OMe)-Glu(OMe)-Asp(OMe)-FMK
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