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Enzymes for Research, Diagnostic and Industrial Use

Celecoxib

Cat No.
CEI-0209
Description
Celecoxib
CAS No.
169590-42-5
Molecular Weight
381.37
Purity
>99%
Storage
2 years at -20centigrade Powder
Targets
Cyclo-oxygenase 2
Molecular Formula
C17H14F3N3O2S
Solubility
DMSO 76 mg/mL, Water
In vitro
Celecoxib is a selective COX-2 inhibitor with IC50 of 40 nM. Celecoxib shows low sensitivity against COX-1 with IC50 of 15 uM. Celecoxib shows an anti-proliferative effect on nasopharyngeal carcinoma (NPC) cell lines including HNE1 and CNE1-LMP1 with IC50 of 32.86 uM and 61.31 uM, respectively.
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