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diguanylate cyclase

Cat No.
EXWM-3276
Description
A GGDEF-domain-containing protein that requires Mg2+ or Mn2+ for activity. The enzyme can be activated by BeF3, a phosphoryl mimic, which results in dimerization. Dimerization is required but is not sufficient for diguanylate-cyclase activity. Cyclic di-3',5'-guanylate is an intracellular signalling molecule that controls motility and adhesion in bacterial cells. It was first identified as having a positive allosteric effect on EC 2.4.1.12, cellulose synthase (UDP-forming).
Form
Liquid or lyophilized powder
Enzyme Commission Number
CAS No.
146316-82-7
Storage
Store it at +4 ºC for short term. For long term storage, store it at -20 ºC~-80 ºC.
Synonyms
DGC; PleD
Reaction
2 GTP = 2 diphosphate + cyclic di-3',5'-guanylate
Notes
This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
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