Products
Online Inquiry
Our Products Cannot Be Used As Medicines Directly For Personal Use.
Welcome! For price inquiries, please feel free to contact us through the form on the left side. We will get back to you as soon as possible.
FAS Inhibitor, C75
Cat No.
CEI-0481
Description
Inhibitor of fatty acid synthase (FAS) reducing food intake and body weight in mice. Exhibits irreversible slow-binding biphasic inactivation of FAS. Down regulates neuropeptide Y and Agouti-related protein expression. Has been proposed to activiate CPT-1 activity in liver and adipose tissue, leading to increased fatty acid oxidation and energy production. Shows significant in vivo antitumor activity in human breast cancer cells.Suppresses DNA replication and induces apoptosis. FAS inhibition by C75 leads to dramatic accumulation of the CDK inhibitor p27KIP1 from cytosol to cell nuclei.
Appearance
White solid
Product Overview
A FAS inhibitor
CAS No.
191282-48-1
Molecular Weight
515.86
Purity
>98% by TLC
Storage
-20 centigrade
Targets
FASN
Molecular Formula
C₁₄H₂₂O₄
Chemical Name
4-Methylene-2-octyl-5-oxotetrahydrofuran-3-carboxylic acid
Solubility
H₂O (100 mM)
Shipping Conditions
RT
Download
Download Datasheet