Products

Enzymes for Research, Diagnostic and Industrial Use

Fingolimod (FTY720)

Cat No.
CEI-0330
Description
Fingolimod (FTY720) can inhibit S1P receptor with IC50 of 0.033 nM.
Alias
Gilenia
CAS No.
162359-56-0
Molecular Weight
343.9
Purity
>99%
Storage
2 years at -20centigrade Powder
Synonyms
Gilenia
Targets
S1P receptor
Molecular Formula
C19H33NO2.HCl
Chemical Name
2-(4-octylphenethyl)-2-aminopropane-1,3-diol hydrochloride
Solubility
DMSO 69 mg/mL Water 69 mg/mL Ethanol 69 mg/mL
In vitro
FTY720 is a S1P receptor inhibitor and it can inhibit S1P receptor with IC50 of 0.033 nM. Fingolimod represents a new generation of immunosuppressant that modulates lymphocyte trafficking by interacting with the S1P (sphingosine-1-phosphate signaling) receptor, which plays a key role in the development of immunological and neurological components of multiple sclerosis (MS).
In vivo
FTY720 induces apoptosis in prostate cancer cells by inhibition of SphK1. Research finished MTT assay and find that FTY720 induced apoptosis in PC-3 cells.
Download Datasheet:



Inquiry
Online Inquiry
Name:
*Phone:
*E-mail Address:
Country:
Company/Institution:
*Products or Services Interested:
Quantity:
Project Description:
Our Products are Not Intended for Private Therapeutic Use!
*Verification Code:
Please input "enzymes"(case insensitive) as verification code.

Welcome! For price inquiries, please feel free to contact us through the form below through the form on the left side. We will get back to you as soon as possible.

Sitemap  Privacy Policy
Copyright ©2011 - 2017 Creative Enzymes.
Contact Us 45-1 Ramsey Road, Shirley, NY 11967, USA
Email: info@creative-enzymes.com
Tel: 1-631-562-8517 1-631-448-7888
Fax: 1-631-938-8127
Distributors To view the contact information for a specific location, select the desired country: