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GNE 477

Cat No.
CEI-1138
Description
GNE 477 is a potent and efficacious dual PI3K/mTOR inhibitor with an IC50 value of 4nmol/L and 21nmol/L respectively.
Abbr
GNE 477(PIK3CA, MTOR)
Alias
CLOVE, CWS5, MCAP, MCM, MCMTC, PI3K, p110-alpha
CAS No.
1032754-81-6
Molecular Weight
504.63
Purity
> 95%
Stability
2 years -20 centigrade Powder
1 month -4 centigrade in DMSO
More than one month -80 centigrade in DMSO
Storage
4 centigrade
Synonyms
CLOVE, CWS5, MCAP, MCM, MCMTC, PI3K, p110-alpha
Targets
PI3K, mTOR
IC50
4nmol/L, 21nmol/L
Molecular Formula
C21H28N8O3S2
Chemical Name
5-(7-methyl-6-((4-(methylsulfonyl)piperazin-1-yl)methyl)-4-morpholinothieno[3,2-d]pyrimidin-2-yl)pyrimidin-2-amine
Solubility
DMSO > 112mg/mL Water >1mg/mL Ethanol > 4mg/mL
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