Products

Enzymes for Research, Diagnostic and Industrial Use

GW-5074

Cat No.
CEI-0965
Description
Specific inhibitor of cRaf-1 kinase (IC50=9 nM). Acts at > 100-fold selectivity for raf kinase over CDK1, CDK2, c-src, ERK2, MEK, p38, Tie2, VEGFR2 and c-fm. Displays neuroprotective activity. Cell permeable.
Abbr
GW-5074(RAF1)
Alias
3-(3, 5-Dibromo-4-hydroxy-benzylidene)-5-iodo-1, 3-dihydro-indol-2-one
Appearance
Off white powder
Product Overview
c-Raf1 inhibitor
CAS No.
220904-83-6
Molecular Weight
520.9
Purity
98% (TLC); NMR (Conforms)
Synonyms
3-(3,5-Dibromo-4-hydroxy-benzylidene)-5-iodo-1,3-dihydro-indol-2-one
Targets
c-Raf1
Molecular Formula
C15H8Br2INO2
Melting Point
267-268ºC
Solubility
May be dissolved in DMSO (50 mg/ml)
Download Datasheet:



Inquiry
Realted Products
Catalog
ProductName
EC No.
CAS No.
Source
Price
CatalogCEI-0148
ProductNameZM 336372
EC No.
CAS No.208260-29-1
Source
CatalogCEI-0149
ProductNameSB590885
EC No.
CAS No.405554-55-4
Source
CatalogCEI-0156
ProductNameGDC-0879
EC No.
CAS No.905281-76-7
Source
Online Inquiry
Name:
*Phone:
*E-mail Address:
Country:
Company/Institution:
*Products or Services Interested:
Quantity:
Project Description:
Our Products are Not Intended for Private Therapeutic Use!
*Verification Code:
Please input "enzymes"(case insensitive) as verification code.

Welcome! For price inquiries, please feel free to contact us through the form below through the form on the left side. We will get back to you as soon as possible.

Sitemap  Privacy Policy
Copyright ©2011 - 2017 Creative Enzymes.
Contact Us 45-1 Ramsey Road, Shirley, NY 11967, USA
Email: info@creative-enzymes.com
Tel: 1-631-562-8517 1-631-448-7888
Fax: 1-631-938-8127
Distributors To view the contact information for a specific location, select the desired country: