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Enzymes for Research, Diagnostic and Industrial Use

INO-1001

Cat No.
CEI-0321
Description
INO-1001
CAS No.
"3544-24-9
Molecular Weight
136.15
Purity
>99%
Storage
2 years at -20 centigrade
Targets
PARP
Molecular Formula
C7H8N2O
Solubility
No
In vitro
INO-1001 can potently inhibits PARP with IC50 of 50 nM.. Inhibition of PARP activity by INO-1001 significantly improves endothelial function by enhancing the acetylcholine-induced, endothelium-dependent, nitric oxide mediated vasorelaxation after exposure with 400 uM H2O2.
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