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IQ-1

Cat No.
CEI-0711
Description
Maintains the undifferentiated state of embryonic stem cells. By targeting the PR72/130 subunit of the Ser/Thr phosphatase PP2A, it prevents β-catenin from switching coactivator usage from CBP to p300. The increase in β-cateinin/CBP mediated transcription at the expense of β-cateinin/p300-mediated transcription helps to maintain the murine stem cell pluripotency.
Appearance
Off-white solid
Product Overview
A stem cell differentiating agent
CAS No.
331001-62-8
Molecular Weight
509.72
Purity
>98% by HPLC
Storage
-20 centigrade
Targets
PP2A
Molecular Formula
C₂₁H₂₂N₄O₂
Chemical Name
2-[(4-Acetylphenyl)azo]-2-(3,4-dihydro-3,3-dimethyl-1(2H)-isoquinolinylidene)-acetamide
Solubility
DMSO (10 mM)
Shipping Conditions
Gel pack
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