Products

Enzymes for Research, Diagnostic and Industrial Use

Itraconazole

Cat No.
CEI-0524
Description
A synthetic broad-spectrum triazole antifungal agent with the mode of action being through Inhibition of cytochrome P450 dependent enzymes including 14α-demethylase. Recently, it has been shown that Itraconazole inhibits Hedgehog (Hh) signaling pathway activity (IC50 = 0.8 µM) as well as blocks the VEGFR2 glycosylation, trafficking, and signaling in endothelial cells.
Alias
Oriconazole, R51211, Sporanox
Appearance
Yellow solid
Product Overview
An antifungal agent and Hh signaling inhibitor
CAS No.
84625-61-6
Molecular Weight
489.99
Purity
>98% by HPLC
Storage
-20 centigrade
Synonyms
Oriconazole, R51211, Sporanox
Targets
Hh
Molecular Formula
C 35 H 38 Cl 2 N 8 O 4
Chemical Name
(2R,4S)-rel-1-(butan-2-yl)-4-{4-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin-1-yl]phenyl}-4,5-dihydro-1H-1,2,4-triazol-5-one
Solubility
DMSO (>20 mg/ml)
Shipping Conditions
Gel pack
Download Datasheet:



Inquiry
Realted Products
Catalog
ProductName
EC No.
CAS No.
Source
Price
CatalogCEI-0518
ProductNameCyclopamine-KAAD
EC No.
CAS No.306387-90-6
Source
CatalogCEI-0519
EC No.
CAS No.330796-24-2
Source
CatalogCEI-0520
ProductNameGANT58
EC No.
CAS No.64048-12-0
Source
CatalogCEI-0521
ProductNameGANT61
EC No.
CAS No.500579-04-4
Source
+ See More >>
Online Inquiry
Name:
*Phone:
*E-mail Address:
Country:
Company/Institution:
*Products or Services Interested:
Quantity:
Project Description:
Our Products are Not Intended for Private Therapeutic Use!
*Verification Code:
Please input "enzymes"(case insensitive) as verification code.

Welcome! For price inquiries, please feel free to contact us through the form below through the form on the left side. We will get back to you as soon as possible.

Sitemap  Privacy Policy
Copyright ©2011 - 2017 Creative Enzymes.
Contact Us 45-1 Ramsey Road, Shirley, NY 11967, USA
Email: info@creative-enzymes.com
Tel: 1-631-562-8517 1-631-448-7888
Fax: 1-631-938-8127
Distributors To view the contact information for a specific location, select the desired country: