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JM6

Cat No.
CEI-0551
Description
Cell-permeable. A slow-release prodrug version of Ro 61-8048, an inhibitor of KMO (kynurenine 3-monooxygenase), the enzyme that controls the kynurenine pathway, long believed to be implicated in neurodegeneration. JM6 reverses and prevents symptoms of neurodegenerative diseases like Alzheimer’s and Huntington’s in animal models. JM6 does not penetrate into the brain, but works by inhibiting KMO in the blood.
Appearance
Liquid
Product Overview
A high-affinity inhibitor of KMO (kynurenine 3-monoxygenase or kynurenine 3-hydroxylase)
CAS No.
1008119-83-2
Molecular Weight
696.7
Purity
>95% by HPLC
Storage
-20 centigrade
Targets
KMO
Molecular Formula
C₂₃H₂₆N₄O₆S₂
Chemical Name
2-(3,4-Dimethoxybenzenesulfonylamino)-4-(3-Nitrophenyl)-5-(Piperidin-1-yl)Methylthiazole
Shipping Conditions
Gel pack
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CatalogCEI-0550
ProductNameRo 61-8048
EC No.
CAS No.199666-03-0
Source
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