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LLL12
Cat No.
CEI-0670
Description
A Stat3 phosphorylation inhibitor. LLL12 inhibits STAT3 phosphorylation (Tyr705) and STAT3 activities and down-regulates STAT3 downstream targets; inhibits proliferation, colony formation, and cell migration and induces apoptosis in various human breast and pancreatic cancer cells as well as in glioblastoma cells. LLL12 has minimal apoptotic effects on normal human cells.
Appearance
Lyophilized solid
Product Overview
A Stat3 phosphorylation inhibitor
CAS No.
1260247-42-4
Molecular Weight
263.26
Purity
>95% by HPLC
Storage
-20 centigrade
Targets
STAT3
Molecular Formula
C₁₄H₉NO₅S
Chemical Name
5-Hydroxy-9,10-dioxo-9,10-dihydroanthracene-1-sulfonamide
Solubility
DMSO (20 mM)
Shipping Conditions
Gel pack
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