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meprin B

Cat No.
EXWM-4346
Description
A brush border membrane-bound metalloendopeptidase known from the intestine of all mouse strains that have been tested, and the kidney of certain inbred strains. A tetramer of meprin β subunits (in contrast to meprin A, which contains both α and β subunits). Occurs in the kidney as a proenzyme that can be activated by trypsin. Meprin B is inhibited by both EDTA and 1,10-phenanthroline, but not by phosphoramidon, captopril or thiorphan. In peptidase family M12 (astacin family)
Form
Liquid or lyophilized powder
Enzyme Commission Number
CAS No.
150679-52-0
Storage
Store it at +4 ºC for short term. For long term storage, store it at -20 ºC~-80 ºC.
Synonyms
meprin-b
Reaction
Hydrolysis of proteins, including azocasein, and peptides. Hydrolysis of -His5┼Leu-, -Leu6┼Cys-, -Ala14┼Leu- and -Cys19┼Gly- bonds in insulin B chain
Notes
This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
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