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Myeloperoxidase Inhibitor

Cat No.
CEI-0580
Description
A potent, irreversible, and specific inhibitor of the peroxidation activity of myeloperoxidase (MPO; IC₂sub>50 = 300 nM). Does not affect catalase or glutathione peroxidase activities. Also displays no effect on the production of superoxide by neutrophils. Shown to inhibit H 2 O 2 -induced apoptosis in HL-60, human leukemia cells.
Alias
4-Aminobenzoic hydrazide; MPO Inhibitor; 4-ABH
Appearance
Yellow to beige solid
Product Overview
A potent myeloperoxidase (MPO) inhibitor
CAS No.
5351-17-7
Molecular Weight
223.35
Purity
>97% by HPLC
Storage
-20 centigrade
Synonyms
4-Aminobenzoic hydrazide; MPO Inhibitor; 4-ABH
Targets
MPO
Molecular Formula
C 7 H 9 N 3 O
Solubility
DMSO or EtOH
Shipping Conditions
Gel pack
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