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Enzymes for Research, Diagnostic and Industrial Use

NIBR-17

Cat No.
CEI-1136
Description
NIBR-17 is a pan class I PI3K inhibitor with IC50 values 0.001, 0.092, 0.009 and 0.020uM respectively for PI3Kα, β, γ, and δ.
Abbr
NIBR-17(PIK3CA, PIK3CB, PIK3CG, PIK3CD)
Alias
CLOVE, CWS5, MCAP, MCM, MCMTC, PI3K, p110-alpha
CAS No.
944396-88-7
Molecular Weight
380.4
Purity
> 95%
Stability
2 years -20 centigrade Powder
1 month -4 centigrade in DMSO
More than one month -80 centigrade in DMSO
Storage
4 centigrade
Synonyms
CLOVE, CWS5, MCAP, MCM, MCMTC, PI3K, p110-alpha
Targets
PI3Kα, β, γ, and δ
IC50
0.001uM, 0.092uM, 0.009uM,0.020uM
Molecular Formula
C18H20N8O2
Chemical Name
5-(6-(6-methoxypyridin-3-ylamino)-2-morpholinopyrimidin-4-yl)pyrimidin-2-amine
Solubility
DMSO > 112mg/mL Water >1mg/mL Ethanol > 4mg/mL
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